Md. Khademul Islam

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Name: 
Md. Khademul Islam
Position: 

Lecturer

Personal Contact: 

Department of Genetic Engineering and Biotechnology
University of Dhaka
Dhaka-1000, Bangladesh.

Academic qualification: 

Master in Medical Engineering Science
Yamaguchi University, Japan. Excellent Grade.

MS
Department of Microbiology
University of Dhaka, Bangladesh.

B.Sc. (Honours)
Department of Microbiology
University of Dhaka, Bangladesh.

HSC
Notre Dame College
Dhaka, Bangladesh.

SSC
Govt. Laboratory High School
Dhaka, Bangladesh

Recent Jobs: 

Lecturer: 10th August 2005 to date:
Department of Genetic Engineering & Biotechnology
University of Dhaka.

Visiting Scholar :1st January 2010 to 30th June 2010
Department of Biochemistry and Molecular Genetics
University of Illinois, at Chicago (UIC), USA.

Visiting Scholar: 2nd July to 30th September 2008 Barcelona Biomedical Research Park (PRBB)
Barcelona, Spain.

Visiting Scientist: 10th July 2006 to 31st September 2006
Department of Bio-Signal Analysis
Applied Medical Engineering Science
Graduate School of Medicine
Yamaguchi University, Japan

Lecturer: March 15, 2005 to August 6, 2005
Department of Microbiology
Stamford University, Bangladesh.

Ongoing research: 
  • Integration of multidimensional OncoGenomics Data for the identification of genes and groups of genes (biological modules) involved in cancer development. (www.intogen.org)
  • Bioinformatic study of genomic alterations in cancer in the context of biological networks such as protein-protein interaction network (PPIN), pathway interaction network (PCN), microRNA-target gene interaction network and gene regulatory network (GRN).
  • PLU1 in Differentiation and Cancer: how the pRB pathway in conjunction with RBP2 and PLU1 (JARID1B) is tied up to differentiation and how deregulation of PLU1/RBP2 activities might be abrogated in cancer.
  • Genetic interaction of RBF and Hippo pathways in Drosophila melanogaster – role in differentiation and cancer.
  • Genome wide expression analysis of microRNA in various mutational conditions (eg, RBF, Hippo, double) in Drosophila melanogaster eye imaginal disc tissue to study their role in differentiation.
  • Role of miR-11 and miR-998 in cell cycle and apoptosis in Drosophila melanogaster Role of tPA in mouse hippocampal neuron – analysis of wnt pathway.
  • p38 MAPK signaling pathway in mouse embryonic fibroblast (MEF) – role of stress response genes and stress activation of p38 MAPK.
  • Integration of clinical data with genome wide transcriptional expression and chromosomal abnormalities (aCGH) in patients with liver cancer.
  • H. pylori molecular epidemiology research in collaboration with Dr. Jamalun Nessa, Department of Microbiology, Dhaka University.
List of publication: 

Full Paper

1. ABM Md. Khademul Islam, Jamalun Nessa, Mahmuda Yasmin, Chowdhury Rafiqul Ahsan. 2002. Seroprevalence of S. flexneri 2a infection in Bangladeshi population and analysis of its relationship with sex, age, blood group, acidity. Bangladesh Journal of Microbiology, 19(1 & 2): 73-77.

2. Jakia Amin, Abul Bashar Mir Md. Khademul Islam and Md. Majibur Rahman.2004. Prevalence and antibiotic resistance of pathogenic microorganisms of poultry products and associated manpower. Bangladesh Journal of Microbiology. 21(2):101-103.

3. ABM Md. Khademul Islam, Mahmuda Yasmin, Jamalun Nessa, Chowdhury Rafiqul Ahsan. 2005. Helicobacter pylori infection in Bangladeshi population: Serodiagnosis, Seroprevalence and Risk factors. The Dhaka University J. of Biological Sciences. 14(1):1-8.

4. Farhana Rahman, ABM Md. Khademul Islam, Jamalun Nessa, Chowdhury Rafiqul Ahsan and Mahmuda Yasmin. 2005. Correlation in Prevalence, Risk Factors and Serological Detection of Helicobacter pylori by Different Techniques. Bangladesh Journal of Microbiology, 22(2):152-157.

5. Md. Shahidul Islam, ABM Md. Khademul Islam, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin and Jamalun Nessa. 2006. Seroprevalence of Helicabacter pylori Among Underprivileged Bangladeshi Children: Case Study in a Day-care Center. Bangladesh Journal of Microbiology, 23(1): 24-28.

6. Khademul Islam, Md. Ibrahim Khalil, Chowdhury Rafiqul Ahsan and Mahmuda Yasmin and Jamalun Nessa. 2007. Analysis of immue responses against Helicobacter pylori in rabbit. World J of Gastroenterology; 13(4):600-606.

7. Saeid Abroun, Ken-ichiro Otsuyama, Karim Shamsasenjan, Abul Islam, Jakia Amin, Michio M Kawano. Galectin-1 supports the survival of CD45RA(-) primary myeloma cells in vitro. 2008. British Journal of Hematology. (2008 Sep;142(5):754-65. )

8. Dey SK, Islam A, Mizuguchi M, Okitsu S, Ushijima H. 2008. Epidemiological and Molecular Analysis of Astrovirus Gastroenteritis in Dhaka City, Bangladesh. Journal of Tropical Pediatrics (2008 Dec;54(6):423-5. )

9. Shuvra Kanti Dey, Hideaki Shimizu, Tung Gia Phan, Yuko Hayakawa, Abul Islam, Abul Faiz Mohammad Salim, Anisur Rahman Khan, Masashi Mizuguchi, Shoko Okitsu, Hiroshi Ushijima.Molecular epidemiology of adenovirus infection among infants and children with acute gastroenteritis in Dhaka City, Bangladesh. Infection, Genetics and Evolution. Article in press. [Accepted 4 February 2009, Available online]

Abstract

1. ABM Md. Khademul Islam, Mahmuda Yasmin, Jamalun Nessa, Chowdhury Rafiqul Ahsan. 2004. Seroprevalence, Serodiagnosis and Risk factor Analysis for Helicobacter pylori infection in Bangladeshi population. Abstract published and presented In: Bangladesh Society of Microbiologist’s 20th Annual conference. Page: 52. Place: Dhaka, Bangladesh

2. Abul Bashar Mir Md. Khademul Islam and SI Khan. 2005. A comparative assessment of phenotypic and genotypic characterization of Shigella spp. isolated from food and clinical samples. Abstract published and presented In: Bangladesh Society of Microbiologist’s 21st Annual conference. Article no. 3.14. Place: Mymenshing, Bangladesh.

3. Md. Ibrahim Khalil, ABM Md. Khademul Islam, Chowdhury Rafiqul Ahsan and Mahmuda Yasmin and Jamalun Nessa. 2006. Analysis of immue responses against Helicobacter pylori in rabbit. Abstract published and presented In: Bangladesh Society of Microbiologist’s 22nd Annual conference. Place: Dhaka, Bangladesh.

4. Saeid Abroun, Ken-Ichiro Otsuyama, Karim Shamsasenjan, Khademul Islam, Jaki Amin, Hideki Asaoku, Michio M. Kawano. 2006. Gelatin-Coated Insert-Well Culture Markedly Improved In Vitro Culture of Primary Myeloma Cells. Abstract published In: abstract book of American Society of Hematology 48th Annual conference. Article no. 5020. Place: Orlando, USA.

5. Ken-ichiro Otsuyama, Jakia Amin, Emi Uchida, Saeid Abroun, Karim Shamsasenjan, Khademul Islam, Hideki Asaoku, Michio M. Kawano. 2006. Baicalein Combined with Dexamethasone Can Induce the Marked PPARß-Mediated Suppression of Growth and Survival in Human Myeloma Cells. Abstract published In: abstract book of American Society of Hematology 48th Annual conference. Article no. 5085. Place: Orlando, USA.

6. Jakia Amin, Ken-ichiro Otsuyama, Emi Uchida, Saeid Abroun, Karim Shamsasenjan, Khademul Islam, Michio M. Kawano. 2006. The Potentials of Constitutive NF-κB Activation in U266 Cell Lines. Abstract published In: abstract book of American Society of Hematology 48th Annual conference. Article no. 5008. Place: Orlando, USA.

7. Karim Shamsasenjan, Saeid Abroun, Shngqin Liu, Jakia Amin, Khademul Islam, Ken-ichiro Otsuyama, Michio M. Kawano. 2006. IL-6 Down-Regulates CD33 Expression in Primary Myeloma Cells as Well as Myeloma Cell Lines. Abstract published In: abstract book of American Society of Hematology 48th Annual conference. Article no. 5009. Place: Orlando, USA.

8. Abul Bashar Mir Md. Khademul Islam, Ibrahim Khalil, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin and Jamalun Nessa. Analysis of Immune Responses Against Helicobacter pylori in Rabbit. 2006. Abstract published in the first International Congress of Central Asia Infectious Diseases (ICCAID 2006) was in Bishkek, Kyrgyz Republic between 30 October-02 November 2006. Page 112, article No. P105.

9. Khademul Islam, Ken-ichiro Otsuyama, Saeid Abroun, Jakia Amin, Karim Shamsasenjan and Michio M. Kawano. 2007. Expression of Chemokine Receptors in Primary Myeloma Cells. Abstract published and presented In: abstract book of 46th Chugoku-Shikoku Meeting in JSH. Article no. 10, page 16. Place: Izumo City, Shimane, Japan. March 2-3, 2007.

10. Jakia Amin, Ken-ichiro Otsuyama, Khademul Islam, Saeid Abroun, Karim Shamsasenjan, and Michio M. Kawano. 2007. NF-κB Activity in Myeloma Cell Lines. Abstract published In: abstract book of 46th Chugoku-Shikoku Meeting in JSH. Article no. 11, page 17. Place: Izumo City, Shimane, Japan. March 2-3, 2007.

11. Jakia Amin, Ken-ichiro Otsuyama, Abul Islam, Karim Shamsasenjan, Mohd Shamim Iqbal, Saeid Abroun, and Michio M. Kawano. 2007. The correlation between constitutive NF-kB activity and CD54 expression in human myeloma cell. Abstract published In: abstract book of 69th annual meeting of Japanese society of haematology (JSH). Article no. OS-49-4, page 231. Place: Yokohama, Japan. October 10-12, 2007.

12. Abul Islam, Ken-ichiro Otsuyama, Jakia Amin, Karim Shamsasenjan, Mohd Shamim Iqbal, Saeid Abroun, and Michio M. Kawano. 2007. Biological significance of chemokine receptors expression on human myeloma cells. Abstract published In: abstract book of 69th annual meeting of Japanese society of haematology (JSH). Article no. OS-17-2, page 177. Place: Yokohama, Japan. October 10-12, 2007.

13. Karim Shamsasenjan, Ken-ichiro Otsuyama, Saeid Abroun, Mohd Shamim Iqbal, Jakia Amin, Abul Islam, and Michio M. Kawano. 2007. IL-6-induced down-regulation of CD33 expression in human myeloma cells. Abstract published In: abstract book of 69th annual meeting of Japanese society of haematology (JSH). Article no. OS-16-3, page 176. Place: Yokohama, Japan. October 10-12, 2007.

14. Ken-ichiro Otsuyama, Jakia Amin, Abul Islam, Karim Shamsasenjan, Mohd Shamim Iqbal, Saeid Abroun, and Michio M. Kawano. 2007. The mechanism of PPARb activity to suppress the constitutive NF-kB activity in human myeloma cells. Abstract published In: abstract book of 69th annual meeting of Japanese society of haematology (JSH). Article no. OS-17-5, page 178. Place: Yokohama, Japan. October 10-12, 2007.

15. Mohd Shamim Iqbal, Ken-ichiro Otsuyama, Karim Shamsasenjan, Saeid Abroun, Jakia Amin,Abul Islam, and Michio M. Kawano. 2007. Biological significance of CD56 expression on human myeloma cells. Abstract published In: abstract book of 69th annual meeting of Japanese society of haematology (JSH). Article no. PS-1-53, page 231. Place: Yokohama, Japan. October 10-12, 2007.

16. Ken-ichiro Otsuyama, Jakia Amin, Saeid Abroun, Abul Islam Karim Shamsasenjan, Mohd Shamim Iqbal, Michio M. Kawano. 2007. The PPARß activation mechanism which suppresses the constituitive NF-kB activity in human myeloma cell lines. Abstract published In: abstract book of American Society of Hematology 49th Annual conference. Place: Atlanta, USA. December 8-12, 2007.

17. Jakia Amin, Ken-ichiro Otsuyama, Abul Islam, Karim Shamsasenjan, Mohd Shamim Iqbal and Michio M. Kawano. 2007. The mechanism of Constitutive NF-κB Activity in myeloma Cell Lines. Abstract published In: abstract book of American Society of Hematology 49th Annual conference. Place: Atlanta, USA. December 8-12, 2007.

18. Karim Shamsasenjan, Ken-ichiro Otsuyama, Mohd Shamim Iqbal, Saeid Abroun, Jakia Amin, Abul Islam, Michio M. Kawano. 2007. IL-6 induced c-myc down regulates the expression of CD33 in CD33(+) myeloma cell lines. Abstract published In: abstract book of American Society of Hematology 49th Annual conference. Place: Atlanta, USA. December 8-12, 2007.

19. Mohd Shamim Iqbal, Ken-ichiro Otsuyama, Karim Shamsasenjan, Saeid Abroun, Jakia Amin, Abul Islam, Michio M. Kawano. 2007. The expression of CD56 is frequently accompanied with the expression of neuronal cell markers and its down-regulation is induced by IL-6 in human myeloma cells. Abstract published In: abstract book of American Society of Hematology 49th Annual conference. Place: Atlanta, USA. December 8-12, 2007.

20. Abul Islam, Ken-ichiro Otsuyama, Jakia Amin, Saeid Abroun, Karim Shamsasenjan, Mohd Shamim Iqbal, Michio M. Kawano. 2007. SDF-1 is responsible for the constitutively high NF-kB activity in human myeloma cells. Abstract published In: abstract book of American Society of Hematology 49th Annual conference. Place: Atlanta, USA. December 8-12, 2007.

Trainings: 

1. Proteomics and Structural Genomics of Membrane Proteins: (27/3/06 to 31/3/06). workshop organized by Groningen Biomoleculr Sciences and Biotechnology Institute (GBB), University of Groningen, the Netherlands.

2. Molecular techniques in Aquaculture and seafood safety: (13/2/06 to 17/2/06). FAO, UNESCO, ASM sponsored International workshop on “Molecular Techniques in Aquaculture and Seafood Safety” organized by Department of Fishery Microbiology, Karnataka University, Mangalore, India.

3. Molecular Ecological Techniques: (4/12/04 to 8/12/04). training program on Molecular Ecological Techniques jointly organized by University of Bergen, Norway and Department of Microbiology, University of Dhaka, Bangladesh.

4. Proteomics and System Biology: (31/3/06 to 5/4/06). Visited Professor Peter JF Henderson’s Laboratory in the Institute of Membrane & System Biology, University of Leeds, UK to have basic training & knowledge on bioinformatics, proteomics and system biology tools & techniques.

5. Meetings of Nobel Laureates: (1/7/07 to 6/7/07). 57th Meetings of Nobel Laureates in Medicine at Lindau, Lake Constance, Germany.

6. Embo Practical course on Networks in Biology analysis, modeling and reverse engineering, Bologna Italy 22-25 September 2009.

Awards and achievements: 
  • “Sumitomo Corporation, Japan” scholarship for outstanding academic performance in the faculty of biological science, University of Dhaka.
  • “Provost Award 2003” for achieving highest grade result in B.Sc.
  • “Sushikha Barsha-2003 Gold Medal award” Dhaka University, Bangladesh, for outstanding performance in B.Sc.
  • Government Distinct Merit Scholarship for M.S. study at Dhaka University. (2004)
  • “Honours Scholarship” for excellent academic performance in Master degree in Yamaguchi University, Japan (2006-2007).
  • Human Frontier Science Program (HFSP) grant scholarship to work as visiting scholar in Bioinformatics and Oncogenomics, in the Barcelona Biomedical Research Park, University Pompeu Fabra, Spain.
  • FI-Modalitat-B, Genaralitat Fellowship from Spanish Government (Catalan) for PhD study in University Pompeu Fabra, Spain.
  • AGAUR Modalitat-A: Fellowship from Spanish Government (Catalan) to do research (visiting scholar) for 6 months (January – June 2010) in the Department of Biochemistry and Molecular Genetic, University of Illinois at Chicago, USA.
  • EMBO fellowship to participate EMBO Practical course on Networks in Biology analysis, modeling and reverse engineering, Bologna, Italy (22-25 September, 2009)
Membership: 
  • Bangladesh Society of Microbiology (BSM).
  • Japanese Society of Hematology (JSH).